Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the acf domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /var/www/dev/wp-includes/functions.php on line 6121

Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the wpmf domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /var/www/dev/wp-includes/functions.php on line 6121

Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the pb-seo-friendly-images domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /var/www/dev/wp-includes/functions.php on line 6121

Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the rocket domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /var/www/dev/wp-includes/functions.php on line 6121

Deprecated: Optional parameter $needle declared before required parameter $stuff is implicitly treated as a required parameter in /var/www/dev/wp-content/themes/em-base/core/functions/helpers.php on line 78

Notice: 函数 _load_textdomain_just_in_time 的调用方法不正确acf-font-awesome 域的翻译加载触发过早。这通常表示插件或主题中的某些代码运行过早。翻译应在 init 操作或之后加载。 请查阅调试 WordPress来获取更多信息。 (这个消息是在 6.7.0 版本添加的。) in /var/www/dev/wp-includes/functions.php on line 6121

Warning: Undefined array key 0 in /var/www/dev/wp-content/themes/frontage-labs/core/functions/roles.php on line 81

Notice: 函数 acf_get_value 的调用方法不正确Advanced Custom Fields PRO - We've detected one or more calls to retrieve ACF field values before ACF has been initialized. This is not supported and can result in malformed or missing data. Learn how to fix this. 请查阅调试 WordPress来获取更多信息。 (这个消息是在 5.11.1 版本添加的。) in /var/www/dev/wp-includes/functions.php on line 6121
DMPK
DMPK

成熟的技术和一流的方法

DMPK

药物代谢和药代动力学(DMPK)

在方达,我们的科研人员应用最先进的技术和一流的方法为药物发现和开发过程中的关键里程碑和决策生成数据。训练有素且经验丰富的科学团队就适当的研究设计、研究执行和数据解释向客户提供广泛而深入的专业知识/建议。我们为正在开发的新化学实体和化合物提供广泛的药物代谢和药代动力学能力。我们提供高质量关键 DMPK 数据集的快速周转,以支持在推进潜在治疗剂以进行进一步开发方面的关键决策。

DMPK 能力

方达拥有一系列能力和经验来支持候选药物的发现和开发。

DMPK 表 - DMPK

体外 ADME 和体内研究

  • 体外服务:
    • 体外 ADME 筛选
    • 体外 ADME 发展研究
  • 体内服务

代谢物合成和放射性标记/同位素服务 

  • 用于代谢研究的稳定同位素合成和作为 GLP 生物分析研究的内部标准
  • 代谢物标准的合成(化学或生物)
  • 代谢物鉴定

QWBA 研究和剂量学

QWBA 研究旨在评估从动物组织中消除总放射性的时间过程。从 QWBA 研究中获得的组织分布数据将用于支持监管提交、发现项目,并在向人类研究对象施用放射性标记药物之前提供监管机构和机构审查委员会所需的剂量学计算。

IMG 1906 1024x768 - DMPK

人体放射性标记研究 (hAME) 

综合研究,包括放射性标记化合物的生命周期管理、样品收集、质量平衡、总放射性和测试化合物的药代动力学,以及血浆、尿液和粪便中的代谢物分析。研究是与 Frontage Clinical Services 合作进行的。

 

zh_CNChinese