Mass Spectrophotometry
Our laboratories are equipped with state-of-the-art bioanalytical instruments and software programs for efficient handling of challenging bioanalytical projects. We offer a broad array of small molecule bioanalysis services.
Our Small Molecule Bioanalysis Services Include:
• Method development, transfer and validation
• Sample Analysis
• Nonclinical toxicokinetic /pharmacokinetic screening
• Clinical PK/bioavailability studies
• Bioequivalence studies
• Therapeutic drug monitoring studies
• Drug-drug interaction studies
• Protein binding studies
• Tissue analysis
Our expertise extends to projects that combine small and large molecule bioanalytical activities such as protein, antibody, antibody drug conjugates and biomarker analysis for small molecule drug candidates.
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From method development or transfer and validation to sample analysis and reporting, Frontage’s bioanalytical team has earned a reputation for consistent and high-quality delivery, project after project. With over 66 LC-MS/MS instruments available for methods development, validation and sample analysis, we have the capacity and expertise to meet study timelines.
Expertise in a Wide Range of Techniques and Processes
Method Development, Transfer, and Validation
- Small Molecules
- Peptides
- Proteins
- Labile
- PEG-ylated
- Liposomal
- ADC’s
- Oligo’s
- Chiral
- Deuterated
- Elemental (Metals)
- Nicotine
- All biological matrices
Sample Analysis
- Preclinical PK/TK and All Clinical Studies
- DDI
- BA
- BE
- Protein binding studies
- Biomarker studies
- Pediatrics
- CMS/DBS
- Tissue
Quantitation of Complex Compounds
At Frontage we support clients with challenging and unique studies. We have extensive experience with Liposomal and encapsulated drugs, PEG-ylated compounds, oligos, ADC, ADA and Mab.